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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b3d85a88738b00d8ec66ba0682653e11acf3a10c84effdbddcfd2b7faef1c43' 
  AND token = 'dfTVvb6HRTUKZZCym6EANP3PVE355iT4LMdnAxot1xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}