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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21998105bf119cfab1ec438e73a0987513e9976022faded4e4487d0f06dab647' 
  AND token = 'vMsAqeYzuqo3dO/GI/NFSeolZ/r6naZESoJBsaDdNQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}