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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8ce1a73f07943822c875121e37ade3025fee856a1fd557774e704a301ec2bf' 
  AND token = '4iTw2Jx+CbtK+7XImhv6pQPzkoZTL1iDZ0t0gVxI1Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}