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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6ec1977ccecc79f900b4093e30315bea02805f1a354e5b065c416cb5dee0eb' 
  AND token = 'NAbdHt1ELc+3d+aDrGb3Lk6jFK+Z3nzTKiey7SvXCbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}