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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3e8774cd4126444024409a8a909a131c2d1ddd06c386bf6fcbf60cd8bf02e7' 
  AND token = 'omt8e7k/T/VEqHrC+eDAOkZphDO/uB+sRGXHfQIpwFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}