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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ddb95930a84ea336257758c47ce6c59ccc48236f3c3d5e026fc4e3ef1f935aa' 
  AND token = 'zPf2PFTXUjFusFsDd0ypE7EpDx9xMdWkIU2lbw0/NCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}