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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453ce89d61c36e7e39ee9bd0a96cc7da31efcbd06931c5e81f07891e17eaad7d' 
  AND token = 'btzwe15WsU9LwTsi9NtcE37BawStubtPtPiD8rNI4oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}