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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ca4c1d80bfbc16a8015a901aa143c321f9840d8b55a29cae176c19018a3b6b' 
  AND token = 'bEEFNP5MWKKHmDta1+u0qFsO8exUHLplHlKuWkDQaaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}