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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df2ecc265dc6ee5e3de36d3b659d9051295ab2f29b46868b212af169953e571' 
  AND token = '88WxIqN+D4Qbs9IfNFFxy1Q2OG0GsXQBX6VhJVuMkJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}