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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca06ef0c75661b566565ec799bc0c63a00bbf07dcee0725aabc91afef65927fe' 
  AND token = 'cnagIACfRs4FcrVwYUN8ho/f1UKCL5OlZZnt3UqQBi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}