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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bca8e0a58ee80275e2c36eba1aa01cd550a87f86e3f48e6c5a28015f1bc2691' 
  AND token = '6TpXYUSfYtLvE2XiGsJ+rOpXSt4YTU0NkS7DOO9Tbtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}