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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '169c0a73e87809887e0770a5ee16e6015d8069b68f45ad59ee4d6f4d62ca5b2e' 
  AND token = '+E6lh0L2GAT3hYX11JOtPbRrkH1xZ8VT8/P7RQfC87U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}