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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1794e08e44f1a81af4dd574f201193019ac4bf0ea7e24141cf7a9e88d4cd08a' 
  AND token = 'EF1kUZqIeUYgzZzyoeWfjjZx4CvtCUno6GRjUTbC5ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}