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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bc3e41febd108ffecb44847fa2b6f2a1201c877c23033403dd7d35f78716320' 
  AND token = 'uGYaPPTmn5pnrJqO4I5hu5RnHOeBqMee55SfkeWRdGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}