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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215cf76b756b311853f6343689acea3fa78b42c7f2e2f1481606e2a3c20839f6' 
  AND token = 'yaIUsKOUuIsWejcRKEaoS1XMu518blnzbj65ES3cjZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}