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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250d2dbe8a648aeba03ffd04086b8e0db16235c84e5cde0e4dac0b1867703b49' 
  AND token = '41J41afF3WP+j1J/sc+m/mZkxOXouYfrDdXeYGqZxTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}