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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00027d1672a040df26b54d3c2e14df8c2312eba5500ba79c1dbcec4052266dd3' 
  AND token = 'i06tEFWm1lnyr3R5JWQzP90CB65Th1jAY1uqmJ7RXMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}