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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2caeb9b8baef6f4c031521f3b5c6485c5cd20d5ab4126ee225dc13dcc34280c5' 
  AND token = 'RIQ+oLdT9v/Z08xFwF9oLklTwOjhXFR0GPtkxIt3i4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}