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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db1462e57ad08a402197d02160cf3897dcd8d82e2612db1591b6a2511880d83' 
  AND token = 'Vw/fI/vves45ehh1H+MY2Utk46pXG2un/2ReaAvRHrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}