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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f548a36fb99ebf6b3c539ac4b572007e27ea77ab4afee475d17387a5dc29deba' 
  AND token = '1b4uVbON04zEMfmNIDTo+sqhKIZuN2ZnY/zIWSo+z4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}