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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eacfab9c5bce0532046c54d9599e60d17e79d36192e5bcb8793ef408642b062' 
  AND token = 'kel4pVXTX+cM2A8JveDJ9cDrBrQyah7MMOCaBHrKz2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}