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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f8991f75b5d5e872f36f4146a976e0c6c26f2d4dc06cf920c2d2c269d94b3d0' 
  AND token = '9isIiLOqvVt9Ef+kElIvzEB1P52c8RyUE/gKCnrHbRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}