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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1c80c7d225b75df846bc6e8df2b8401ca84177cc813e745de9ba9b889b8145' 
  AND token = 'bdJRuqFkNuKbiry9H3bxmPF9euRP210T4QXK3P60vEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}