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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e151d92ba8d36da8a35ea76ec6093eb03ee0927dca006af486c261be3a263e2' 
  AND token = 'lxUyrPI+3lYT3kSMR+QiF5j9KDl5RHkKGyu61ZY6nzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}