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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d11b90de528fd0ce48c4bdba3c0cab154536e5a32544edc93b96982fe9c5039' 
  AND token = 'wg2jlwZPPCAoh2K/KQ4wlAfCkOs5ZJtFjqFg1eRVdME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}