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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d2a179aec85199a0d7cc0f8b96b7fe72a7598416e57fb580ad8893ba07a9df' 
  AND token = 'USZy0snE+WSxfTwpY8GKaAZgqFzqkclsU0w88ABS0fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}