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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12526ced2a63cc9349ae64454aaeab696b5c6269b8afc1bc3121eda24d9fadd0' 
  AND token = 'KIiji/7IoCjG4HGVTbqRoxjvEe1XZA92WExxfIj2Fe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}