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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9170392700068278adca603e3113f9c6564303a6fce1842b7f4927ead9c140f3' 
  AND token = 'mU8kDR462MVai2R1Wo1L2JUKBCsRNjEeujAOBJ5uDZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}