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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '466d65ef76004b53b3067002b02771656ef584fcd8170aee74a92fa8e55316f9' 
  AND token = 'cDx9KdSou4Q1S/dYk2TP+0A1r+/p8tVvVbEqyrBP0nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}