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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a63d69d9f39eec88349e7066828be4a21a1cc17a4cb13e3ed81cb9353f799d72' 
  AND token = 'PdvtdqFyYwvCm54Bw+QZDU6H5FwqF6wAdDviy99oHaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}