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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e587218103597b00d5b3a627447518461214cbfb21f95c851d1ff94c09a84a2' 
  AND token = 'xg2SHAp9l7v3XLIb+M09Q++avj5ZY09kU7890Z7bTRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}