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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64630e7b8423f94cda79326f1b8db7cbce7a87b6eb2e6724403307370434c0d4' 
  AND token = 'T9pv31Q+Lp7r1yMwjJG4lZRNBdELfzZOWHsT9zAe0HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}