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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42d8f3b8565d8aa5c3b764abc642e715aac2c0bb6a094376c51b903672e0dbd' 
  AND token = 'IiInJAhrdUiSt3CLxW6i7kI8HAXvQ59IRXNBciOaMEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}