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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee7949582a603e66a7ba30a37bdebb6342a603b6ff830021044bba7786a1680' 
  AND token = 'wYj1WWGjfGzbBwZ1s4TAttZvfVgxPmBPIkJ6po0/uxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}