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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb1cd330c8ce940060b056ddd44135bc7644f82dcfb96e00f4f064f4ef6db111' 
  AND token = 'lA63KRH+l196Pq7VvKLfBvgq7/REg639HNOg3dw8ynI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}