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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d0389a7fcc8b5657f4806d3f58842fe44d0455f0a20dc03108d5107d0c42cc' 
  AND token = 'qINGz6h26HXOEn4EV25YZ7tcbcaMInYuwRRntG+n5hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}