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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd5a6d9768ea264010eaef1ec327f7f307bd70cb2abe586493861cb9d7fb0e6' 
  AND token = '6TuqYKSfoPr6cKJ9VAznJC0YuYOvdh2V1Y6Px4QfUqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}