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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71194c9a64bdac59730afed86317bca37b1655bf63eb53d1b09d7b25372ed866' 
  AND token = 'X6NKtUyd1NlEXEP9/o1+l3OmtIuYfJ7NWzpZ3lmSGG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}