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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4e35ba7a82fcc4e6a49a09c34be44c54a3b20036c79246b43dfa8514ac0883' 
  AND token = 'tMa9J8PSmyTvm2ZgvP2trdUki1/oSmd/MPOnA3NitIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}