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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c5acbf54e859985eb0e87f3636cb46107a42b1e5a2cbeaaaa02fed117d0e52' 
  AND token = 'PcjghhbGGYq2I5MUHriGCvd/u3aigck4rmXCwzkRoeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}