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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9448a73ab965078b3b2a7e012064b00a547e6e275bd2d3c8a01f49affabb6693' 
  AND token = 'C7t1AHCVEFsDjcLEbPY+jCH4i1GF+OlJehQo2vPC8dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}