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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53ae7d29960fa8159b7261f75850084e020cd0f916a89ba67e14d0b6ff247e1' 
  AND token = '2sFDSriRvKgNs2YSS+DzWaCpL7/oK9MIMQQBblhqFsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}