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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d2c07c8bdada2356be92efaa09acac505bbc532c55a9bb02909e23f3d69fa1' 
  AND token = 'DDf4CreK/WCC4Ogqwp1f4+QVesa7mVSUFatNQ6QeicI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}