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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87cd4d5a1e29a7c26906ddd0743f6d9fd1b2da4a062c08bf0fd376542f761f14' 
  AND token = 'oTTL000yxdjpfAYxQ1jrOIOQVvOtGldq9ZmkRzJyWC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}