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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '809a3c0022697959f9d6e1cef561f98e8a33ea572d4ef9b7d3c96b880678bbbf' 
  AND token = 'rLmTfxkoOB3Z2lMqdal+qSCJUoQ4CZGjoLOo0eotVPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}