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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '957387df8f7a91634431f92984d9405855b7bf15598d73d729c2f77bacac2011' 
  AND token = '2YpOGXWD4NvcTi3CI+fdiaVuVgg5wOgV1iXo8GwTz70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}