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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe9cf5c60648f59a48b81b653c15cb0d5aa8ddaf49a64c10553fcb0cff1f69d' 
  AND token = 'jtXkheH4ETTG/fpeUho5ijBWc07+Sx9tO5Ccj9qBPvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}