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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff28290cb1aeb52dab43724c2e15b3110403264fe7f06b49176a60029a437fd1' 
  AND token = 'wdQbZ43+E+/WVk2fIUDfnuqVtJsK2xquA2M6IT8S1Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}