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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d85b12f07704bfefe6a5cf605210e5c61501f98488ccce5aa1eab06c4d774fa' 
  AND token = 'WROBDX1pOGqTdtkSdVmOCLat1AR81sDy7C+Cp5eKVuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}