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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46320f07622970bc9024a4b809ea733ed982f86ec4fb68c8764f22e4e1104b1' 
  AND token = 'EfWoic3TcH0UGLQ1do3EVPlGqD2lBCPcjk0qSwJmBXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}